The study reveals that APOE4, a genetic risk factor for Alzheimer’s Disease and cardiovascular diseases, has complex effects on mortality risk. While APOE4 carriers with higher AD neuropathology have increased mortality risk, those with low neuropathology had a reduced risk of certain cancers, warranting further research into this genetic factor’s diverse impact on health outcomes.
Social relationships buffer the effects of negative childhood experiences on frailty
Frailty is a serious concern in later-life adults due to its association with additional health risks including disability, falls, hospitalization and mortality.
September 22, 2023