Competitive pressure and a pause in manufacturing due to routine maintenance have pushed US sales of Abecma (idecabtagene vicleucel), Bristol Myers Squibb and 2seventy bio’s CAR-T cell therapy for multiple myeloma, to new lows, causing BMS to miss Wall Street’s quarterly expectations by about $40 million and 2seventy’s stock $TSVT to drop by 24% in afternoon trading.
The announcement from Bristol Myers, which equally shares Abecma with 2seventybio, on lackluster sales pushed 2seventy — which does not announce its quarterly results until Nov. 14 — to release an SEC filing today making clear that competitive dynamics impacting Abecma are here to stay, and “will continue into the fourth quarter of 2023.”
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