GlobalData tracks drug-specific phase transition and likelihood of approval scores, in addition to indication benchmarks based off 18 years of historical drug development data. Attributes of the drug, company and its clinical trials play a fundamental role in drug-specific PTSR and likelihood of approval.
LOXO-783 overview
LOXO-783 (LOX-22783) is under development of the treatment of ER positive human epidermal growth factor receptor 2 negative breast cancer (HER2- Breast Cancer) and solid tumor. It is a mutant-selective and brain-penetrant allosteric PI3Kalpha H1047R inhibitor. It is administered through oral route in the form of tablet.
Loxo Oncology overview
Loxo Oncology a biopharmaceutical company that carries out the development of targeted small molecule therapeutics for the treatment of cancer. The company’s lead product includes IDH1/2 INHIBITOR, FGFR3 SELECTIVE, KRAS G12C INHIBITOR, Next-Gen RET INHIBITOR, PI3Ka INIBITOR and among others provides treatment for cancers. It also offers the ABEMACICLIB treats castrate-resistant prostate cancer, SELPERCATINIB 1L Medullary treats thyroid cancer, ABEMACICLIB treats hormone-sensitive prostate cancer. It is also developing a pipeline of additional product candidates targeting cancers driven by genetic alterations. Loxo Oncology is headquartered in Stamford, Connecticut, the US.
For a complete picture of LOXO-783’s drug-specific PTSR and LoA scores, buy the report here.
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GlobalData’s Likelihood of Approval analytics tool dynamically assesses and predicts how likely a drug will move to the next stage in clinical development (PTSR), as well as how likely the drug will be approved (LoA). This is based on a combination of machine learning and a proprietary algorithm to process data points from various databases found on GlobalData’s Pharmaceutical Intelligence Center.