Researchers from the Perelman School of Medicine at the University of Pennsylvania have invented a new way to map specific DNA markings called 5-methylcytosine (5mC) which regulate gene expression and have key roles in health and disease.
Researchers uncover why the TP53 gene is especially prone to mutations in cancer
Mutations in the fragile TP53 gene impair p53’s tumor-suppressive functions, making it more vulnerable than other tumor suppressors.