Devices Flop for Severe PAD; CPR on LVAD Patients; Cancer Drugs for Heart Disease?

For patients with peripheral artery disease (PAD) and chronic limb-threatening ischemia, drug-eluting stents and drug-coated balloons did not improve amputation-free survival compared with balloon angioplasty alone in the BASIL-3 trial. (TCTMD)

The American College of Cardiology announced that a 90-day comment period is now open for the new Board of Cardiovascular Medicine. The first 10 directors have been selected.

The American Heart Association applauded the Department of Agriculture’s move to limit added sugars in school meals, but called out the lack of restrictions on sugary cereals and donuts.

Heart failure mortality is now worse than it was in 1999. (JAMA Cardiology)

Chest compressions did not appear to hurt patients with a durable left ventricular assist device (LVAD), nor did they dislodge devices. (JACC: Heart Failure)

Could niraparib (Zejula) and other anti-cancer drugs counteract the tumor-like mechanisms driving atherosclerosis? (Circulation)

Penumbra announced the FDA clearance and launch of Lightning Flash 2.0, a computer-assisted vacuum thrombectomy system for removing venous thrombus and treating pulmonary emboli.

Major cardiovascular trials often have event rates and effect sizes overestimated, a systematic review showed. (JAMA Network Open)

Cardiovascular disease and depression share genes and possible development pathways. (Frontiers in Psychiatry)

Air pollution and mental health have a joint impact on death from cardiovascular disease, according to research highlighted by the European Society of Cardiology (ESC).

The ESC also pointed to research that showed that women with heart disease are undertreated with cholesterol-lowering drugs.

Poor cardiovascular health in midlife was linked to declining cognitive processing speeds in Black women. (Journal of the American Heart Association)

Nearly half of men ages 20-44 are believed to have stage 2 or worse cardiovascular-kidney-metabolic syndrome in the U.S. (Journal of the American College of Cardiology)

Testosterone levels in the “high-normal” range predicted an elevated risk of incident atrial fibrillation in healthy older men. (eClinicalMedicine)

Women diagnosed with type 2 diabetes (T2D) and hypertension before age 50 may be a higher-risk group who would benefit from intensive blood pressure treatment. (Diabetes Care)

In patients with T2D and stage 5 chronic kidney disease, use of SGLT2 inhibitors was linked to reduced risks for dialysis and cardiovascular events, an emulated target trial showed. (Annals of Internal Medicine)

New valve surgery risk calculators were launched by the Society of Thoracic Surgeons.

People with Laron syndrome, the rare growth hormone receptor deficiency, have particularly good longevity and heart disease risk factor levels. (Med)

The U.S. Preventive Services Task Force released a draft research plan on the use of coronary artery calcium scoring and ankle brachial index for enhanced cardiovascular disease risk assessment.

Weis Markets stores in Maryland will be equipped with automated external defibrillators ahead of the state’s 2025 deadline for the requirement of such devices in grocery stores and restaurants. (WMAR)

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