Aranscia and SignatureRX Partner to Optimize GLP-1 Medication Use

Aranscia and SignatureRX Partner to Optimize GLP-1 Medication Use

What You Should Know: 

Aranscia, a leader in personalized diagnostics, and Signature RX, a prominent pharmacy supplier, announced a collaborative effort to improve the effectiveness of GLP-1 medications. 

– The multi-phase partnership focuses on developing personalized treatment plans and ensuring consistent access to these crucial medications.

GLP-1s: Beyond Type 2 Diabetes

Glucagon-like peptide-1 receptor agonists (GLP-1s) were initially developed for type 2 diabetes management. However, their use has expanded to other chronic conditions like obesity. While many patients experience success with GLP-1s, individual responses vary in terms of efficacy, side effects, and long-term adherence. This variability can be attributed to unique metabolic responses.

Addressing Challenges in GLP-1 Therapy

The partnership aims to tackle these challenges through several key initiatives:

  • Precision Medicine for GLP-1s: Aranscia’s AccessDx Laboratory will dedicate resources to identifying novel biomarkers and pharmacogenomic (PGx) pathways specific to GLP-1 medications. They will collaborate with relevant organizations to conduct further research and establish frameworks based on these findings.
  • Personalized Medication Management: Signature RX will integrate Aranscia’s YouScript program into their existing offerings. YouScript leverages evidence-based PGx insights to optimize medication use and improve outcomes in patients with various chronic conditions, including those relevant to GLP-1 therapy.
  • Ensuring Medication Availability: The partnership aims to address current and projected shortages of GLP-1 medications, ensuring patients have consistent access to this critical treatment.

“We’re pleased to announce this innovative collaboration with Signature RX,” said Bryon Cipriani, CEO of Aranscia.  “The increasing popularity of GLP-1s, especially when unchecked against inappropriate or ineffective use, leads to runaway cost issues, supply chain challenges, and poor therapeutic outcomes that are detrimental to our care ecosystem.  We’re proud to make a commitment to the exploration of companion diagnostics with AccessDx Lab, and at the opportunity to leverage YouScript’s proven framework for success in personalized medication management.”