Approval in Endometrial Cancer Expanded; Masks at Cancer Centers; NPR Reporter Dies

The FDA expanded the approval of dostarlimab (Jemperli) plus chemotherapy for primary advanced or recurrent endometrial cancer to include patients with mismatch repair proficient/microsatellite stable tumors.

A survey study in Menopause showed that 37% of women were unaware that postmenopausal bleeding is a key symptom of endometrial cancer.

Meanwhile, only 38% of surveyed Americans said they were aware of the availability of lung cancer screening. (American Lung Association)

Seventeen cancer types are more common among Generation X and millennials compared with earlier generations. (Lancet Public Health)

Cholesterol absorption inhibitors may reduce the risk of liver cancer, according to a case-control study. (Cancer)

During last winter’s COVID surge, about 40% of National Cancer Institute-designated cancer centers required universal masking in some clinical areas. (JAMA Network Open)

What will happen with President Biden’s Cancer Moonshot initiative after his time in office? (STAT)

Researchers say they’ve discovered a cause of breakthrough fungal infections for patients undergoing allogeneic hematopoietic cell transplantation. (Nature)

Visceral pleural invasion in non-small cell lung cancer was associated with worse disease- and recurrence-free survival, a secondary analysis of a randomized trial showed. (JAMA Oncology)

More than 11 years after it was published, a Digestive Diseases study linking inflammatory bowel disease to colorectal cancer has been retracted for reported plagiarism. (Retraction Watch)

In a phase II trial of advanced ovarian cancer, an investigational interleukin-12 immunotherapy improved overall survival when added to standard chemotherapy, Imunon announced.

Interim data from a phase III study showed that fixed-duration acalabrutinib (Calquence) plus venetoclax (Venclexta), with or without obinutuzumab (Gazyva), improved progression-free survival in previously untreated chronic lymphocytic leukemia compared with standard chemoimmunotherapy, AstraZeneca announced.

Development of the connective tissue growth factor inhibitor pamrevlumab in metastatic pancreatic cancer will cease after two late-stage trials failed to show an overall survival improvement, FibroGen said.

Long-time NPR correspondent Ina Jaffe has died from breast cancer at the age of 75. (NPR)

Shirley Chung of “Top Chef” said she has been diagnosed with stage IV tongue cancer. (CNN)

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