Millions of older adults may be taking the neuropathy and epilepsy drug gabapentin off-label for everything from itching to alcohol dependence, the New York Times reported.
Also in the New York Times: an update about the mysterious brain disorder in the Canadian province of New Brunswick resembling Creutzfeldt-Jakob disease.
Postmortem tissue showed lecanemab (Leqembi) bound not only to amyloid plaques but to brain blood vessels in people with Down syndrome, raising safety concerns. (JAMA Neurology)
Women were underrepresented at the highest levels of recognition in the child neurology field. (Neurology)
Jean Hébert, PhD, newly hired at the Advanced Research Projects Agency for Health (ARPA-H), is expected to lead a functional brain tissue replacement initiative, which could explore gradually adding bits of lab-made youthful tissue to older people’s brains. (MIT Technology Review)
Researchers identified a new type of network pattern — a barrage of activity originating in the hippocampus — that appeared to balance memory reactivation in mice during sleep. (Science)
Where patients lived was associated with their likelihood of receiving a dementia diagnosis, an analysis of 2018-2019 Medicare claims data showed. (Alzheimer’s & Dementia)
An artificial intelligence model using basic medical and background information showed promise as a screen for autism spectrum disorder. (JAMA Network Open)
A lawsuit alleged that an Atlanta hospital misplaced a portion of a man’s skull that was temporarily removed and scheduled to be reimplanted after an intracerebral hemorrhage. (CNN)
Should the prion paradigm include Alzheimer’s and Parkinson’s disease? (JAMA Neurology)
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