The main text of the study details the experiments conducted to understand the role of IL-24 in AD-like conditions. It describes the methods used, including single-cell RNA sequencing, and the animal models employed to mimic AD. The findings indicate that MRSA infection leads to increased IL-24 in keratinocytes, which in turn heightens type 2 immune responses and worsens AD symptoms.
AstraZeneca, Daiichi Sankyo eye first approval for TROP2 drug after PhIII breast cancer success
AstraZeneca and Daiichi Sankyo’s TROP2-targeted antibody-drug conjugate has met a key endpoint in the Phase III TROPION-Breast01 trial, bringing it one step closer to potentially compete
September 23, 2023