Radiopharm and AtomVie partner on radioantibody development

Radiopharm Theranostics (RAD) and AtomVie Global Radiopharma have announced a partnership for the development and manufacturing of ¹⁷⁷Lu-BetaBart radioantibody to treat multiple solid tumours.

The partnership has been formed with Radiopharm Ventures (RV), a joint venture between RAD and the MD Anderson Cancer Center (MDACC).

¹⁷⁷Lu-BetaBart is a ¹⁷⁷Lutetium-conjugated radioantibody that targets the immune checkpoint molecule B7-H3, which is heavily exhibited in various tumour types and associated with aggressive cancer and poor patient outcomes.

The collaboration intends to strengthen both companies’ expertise to producenew radiotherapeutic solutions for cancer, addressing significant unmet medical needs.

The first targeted radiopharmaceutical against the 4Ig subtype of B7-H3, ¹⁷⁷Lu-BetaBart was engineered at MDACC to have a lesser blood circulation time and decreased on-target off-tissue toxicity.

RAD managing director and CEO Riccardo Canevari stated: “Our collaboration with AtomVie is a significant step forward in our mission to bring innovative radiopharmaceutical therapies to patients.

Access the most comprehensive Company Profiles on the market, powered by GlobalData. Save hours of research. Gain competitive edge.

View profiles in store

Company Profile – free sample

Your download email will arrive shortly

We are confident about the unique quality of our Company Profiles. However, we want you to make the most beneficial decision for your business, so we offer a free sample that you can download by submitting the below form

By GlobalData

Tick here to opt out of curated industry news, reports, and event updates from Pharmaceutical Technology.

Submit and download

Visit our Privacy Policy for more information about our services, how we may use, process and share your personal data, including information of your rights in respect of your personal data and how you can unsubscribe from future marketing communications. Our services are intended for corporate subscribers and you warrant that the email address submitted is your corporate email address.

“Their proven track record in manufacturing and global distribution assures us that we are in capable hands as we progress through the clinical stages and prepare for potential commercialisation.”

The partnership unites RAD’s portfolio of radiotherapeutic products with AtomVie’s capabilities in manufacturing and global distribution of radiopharmaceuticals.

The ¹⁷⁷Lu-BetaBart project is part of a broader pipeline of unique technologies developed by RAD and RV, including small molecules, peptides and monoclonal antibodies, all sourced from universities and institutes worldwide.

AtomVie CEO Bruno Paquin stated: “We are thrilled to partner with RAD on such an important project. With our expertise in radiopharmaceutical manufacturing, we are confident that we can support RAD in advancing its innovative pipeline.

“This partnership reinforces our commitment to transforming patients’ lives with high-quality radiopharmaceuticals, as we continue to expand our capabilities in our new facility and empower novel radiotherapeutics to market.”

A Phase I/II first-in-human trial of ¹⁷⁷Lu-BetaBart across multiple tumour types in the US is anticipated to commence by mid-2025.

Sign up for our daily news round-up!

Give your business an edge with our leading industry insights.