Advanced Adenomas and Early Death; Norovirus Vax Trial Halted; UC and Heart Failure

Advanced adenomas were associated with an increased risk of all-cause mortality, a cohort study from Minnesota found. (JAMA Network Open)

In a very small subset of people with celiac disease, oats can trigger a pro-inflammatory wheat-like response. (Gut)

Four-year results of a phase III trial showed that budesonide oral suspension (Eohilia) for eosinophilic esophagitis was well-tolerated, with about half of patients achieving or maintaining a histologic response. (Clinical Gastroenterology and Hepatology)

A systematic review and meta-analysis in Lancet Gastroenterology & Hepatology looked at non-invasive tests for staging liver fibrosis and cirrhosis in patients with chronic hepatitis B.

Precision BioSciences said its investigational gene therapy for chronic hepatitis B was well-tolerated and demonstrated significant antiviral activity in a small group of patients treated in a phase I trial.

The FDA placed a clinical hold on Moderna’s norovirus vaccine trial following a case of Guillain-Barré syndrome, the company said.

Contrary to expectations, low-dose non-steroidal anti-inflammatory drugs may not reduce pancreatitis risk after endoscopic retrograde cholangiopancreatography, a systematic review and meta-analysis suggested. (BMC Gastroenterology)

Meconium-related obstruction was most likely to occur among preterm infants and those with low birth weight, a large analysis of the National Inpatient Sample found. (JAMA Network Open)

What influence does biological sex have in inflammatory bowel diseases? (Nature Reviews Gastroenterology & Hepatology)

Ulcerative colitis (UC) may have a causal effect on heart failure, according to a Mendelian randomization study. (BMC Gastroenterology)

A Swedish cohort study found that kids with avoidant restrictive food intake disorder had significantly increased risks of being diagnosed with gastrointestinal disorders and various other conditions. (JAMA Pediatrics)

In a Chinese randomized trial, electroacupuncture after laparoscopic gastrectomy for gastric cancer reduced the duration of postoperative ileus compared with sham electroacupuncture or standard of care only. (Gastroenterology)

Investigational NUC-1031 plus cisplatin as first-line treatment of advanced biliary tract cancer failed to improve survival compared with gemcitabine plus cisplatin, a phase III trial showed. (Journal of Hepatology)

Please enable JavaScript to view the

comments powered by Disqus.