This story was corrected to note that Roche has elected not to take its option on SQZ’s program. A previous version said that Roche and SQZ had ended their partnership. This story was also updated with upfront and near-term payment information.
Roche is walking away from its collaboration on SQZ Biotechnologies’ clinical program.
Roche decided not to license and develop SQZ’s antigen presenting cells (APCs) that are designed to spark killer T cells to go after HPV16-positive cancers, the biotech announced Tuesday morning. The program is SQZ’s only APC in the clinic, which it is testing in a Phase I/II study in patients with head and neck, cervical, anal, vulvar, or penile cancers.
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