A First in Total Larynx Transplant; ‘Sniffing’ Out Lung Cancer; Gen X Cancer Toll

A surgical team at Mayo Clinic Arizona in Phoenix performed the first total larynx transplant in an active cancer patient in the U.S. He had lost the ability to speak, swallow, and breathe as a result of treatment for a type of head and neck cancer.

The latest data suggest that 40% of all cancers in people 30 or older arise from potentially modifiable risk factors. (CA: A Cancer Journal for Clinicians)

A dual immunotherapy regimen allowed more than half of patients with one rectal cancer subtype to avoid chemotherapy and surgery that would necessitate use of a colostomy bag. (Vanderbilt University Medical Center)

Preliminary clinical results show that the “E-nose” breath analyzer performed well in detecting lung cancer. (Memorial Sloan Kettering Cancer Center)

Exercise that improves cardiorespiratory fitness might help long-term survivors of childhood cancer avoid treatment-related heart failure later in life, researchers at the University of Alberta said.

Researchers have begun to uncover clues to the striking increases in rates of certain types of cancer in Gen X, born between 1965 and 1980. (JAMA Network Open)

Preclinical studies suggested that stem cell-based therapy might help improve outcomes in the most common form of liver cancer. (Cell Stem Cell)

Early clinical results with skin-targeted photodynamic therapy with synthetic hypericin photosensitizer for cutaneous T-cell lymphoma led to “treatment success” in three of the first four patients who completed treatment, Soligenix announced.

The FDA updated industry guidance to help companies counter misinformation about approved or cleared medical products.

Two commonly used markers of prostate cancer risk — high PSA levels and ≥50% positive biopsy cores — may help identify aggressive cancers within the lowest-risk category. (Mass General Brigham)

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