AI and Mammography; Breast Cancer and Sexual Well-Being; Malaria Drug for Cancer?

Radiologists who used artificial intelligence (AI)-based computer-aided detection for breast screening mammograms detected more cancers with increased recall rates compared with radiologists who didn’t use AI, a prospective cohort study from South Korea showed. (Nature Communications)

The FDA approved tislelizumab (Tevimbra) in combination with platinum-containing chemotherapy for the first-line treatment of unresectable or metastatic PD-L1-positive esophageal squamous cell carcinoma, BeiGene announced.

In other FDA news, the agency scolded Edenbridge Pharmaceuticals for claiming Hemady, its brand-name treatment for multiple myeloma, is more effective than generic versions.

Breast cancer patients who underwent postmastectomy breast reconstruction had lower sexual well-being scores compared with those who received breast-conserving therapy, according to a retrospective study. (Plastic and Reconstructive Surgery)

Based on two decades of data, researchers said that lung cancer surgery has shifted toward less invasive procedures such as segmentectomy and wedge resection. (Duke University School of Medicine, JTO Clinical and Research Reports)

Could pyronaridine, a common malaria drug, be repurposed to fight cancer? (University of Texas El Paso)

Treatment with ¹⁷⁷Lu-edotreotide — a synthetic, targeted radiotherapeutic agent — significantly prolonged progression-free survival compared with standard-of-care everolimus (Afinitor) in patients with grade 1 or 2 gastroenteropancreatic neuroendocrine tumors in the phase III COMPETE trial, ITM Isotope Technologies announced.

Certain co-existing mutations may contribute to resistance to KRAS G12C inhibitors among patients with colorectal and pancreatic cancers, a cohort study showed. (Clinical Cancer Research)

Among phlebotomy-dependent patients with polycythemia vera, 77% of those treated with rusfertide had a clinical response compared with 33% of those who received placebo in the phase III VERIFY trial, Takeda said.

A meta-analysis showed that SGLT2 inhibitors may be heart protective during and after cancer treatment — particularly for breast cancer patients who received anthracyclines. (European Journal of Preventive Cardiology)

Rep. Sylvester Turner (D-Texas), who was sworn into Congress 2 months ago, died at age 70 after suffering a medical emergency. He had undergone treatment for bone cancer in 2022. (Axios)

Five Florida women with breast cancer described their struggles to get their insurance companies to cover treatment. (ABC Action News)

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