Microbiota-reactive T cells trigger colitis in mice harboring the microbiota of wild-caught mice following CTLA-4 blockade, according to a new study that reveals a major mechanism by which anti-CTLA-4 antibodies induce inflammatory toxicities during antitumor immune checkpoint inhibitor therapies.
Make the Diagnosis: He Has Facial Lesions—and So Do Some Teammates. What’s Up?
Presentation A 17-year-old mixed martial arts athlete presented to the doctor with complaints of facial lesions that developed 4 days prior. On examination, discrete and