Autoimmune Afib; Inappropriate ICD Shocks Down; Dissolving Cardiac Sensors

FDA approved expanded use of inclisiran (Leqvio) for primary hyperlipidemia atop its existing indications of atherosclerotic cardiovascular and heterozygous familial hypercholesterolemia, Novartis announced.

An estimate gives users of low-dose colchicine an extra 2 years free of myocardial infarction, stroke, or cardiovascular death in a lifetime. (European Journal of Preventive Cardiology)

A mouse model supports the existence of an autoimmune pathogenesis of atrial fibrillation. (Circulation)

New omnipolar mapping technology produced slightly higher voltages that were helpful for guiding ventricular tachycardia ablation. (HeartRhythm)

In Denmark, people with congenital heart disease are prone to more out-of-hospital cardiac arrest (OHCA), with typical odds of survival. (European Heart Journal)

Bystander response and OHCA survival rates were improved with activation of volunteer responder networks in several European regions. (Journal of the American College of Cardiology)

Contemporary implantable cardioverter-defibrillators carry a low risk of inappropriate shocks, at 1.6% in 2 years, based on postmarketing data. (EP Europace)

The MIB1 gene was identified as having a role in whether a person develops a bicuspid aortic valve. (JAMA Cardiology)

One-year outcomes of taking direct oral anticoagulants or vitamin K antagonists after transcatheter aortic valve replacement were comparable in a real-world German population. (Heart)

An artificial intelligence model has been taught to identify low ejection fraction and various types of valvular heart disease based on chest X-rays. (The Lancet Digital Health)

Separate from socioeconomic status, population well-being was independently associated with cardiovascular outcomes. (JAMA Network Open)

Black women with a history of hypertensive disorders of pregnancy have an estimated 66% higher long-term risk of stroke. (NEJM Evidence)

Tenecteplase (TNKase) performed comparably to alteplase in the subset of stroke patients with large vessel occlusions in the ACT trial. (JAMA Neurology)

At least 3 months after COVID-19 hospitalization, people still had excess emergency visits or hospitalizations for cardiovascular diagnoses, according to records from Alberta, Canada. (JACC: Advances)

Health Canada declared a shortage of dipyridamole, forcing patients to put off myocardial perfusion scans. (CBC News)

Four years after lower-extremity femoropopliteal peripheral intervention for intermittent claudication, the incidence of repeat revascularization rose to 16.7%, and amputations grew to 4.3%. (JACC: Cardiovascular Interventions)

Scientists report how they created a dissolving cardiac device, roughly the size of a postage stamp, that can temporarily perform electrical mapping and pacing. (Science Advances)

Researchers found that impaired heart rate variability in sepsis can hinge on reduced responsiveness of cardiac pacemaker cells. (PNAS)

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