Coffee intake and caffeine metabolites in plasma samples were inversely associated with incident Parkinson’s disease. (Neurology)
A Mendelian randomization study did not find a causal relationship between Parkinson’s and irritable bowel syndrome. (NPJ Parkinson’s Disease)
The U.K.’s Alzheimer’s Society launched a controversial new ad that depicted a “brutally honest” view of dementia. (The Guardian)
Eisai and Biogen submitted a supplemental biologics license application for subcutaneous maintenance dosing of their Alzheimer’s drug lecanemab (Leqembi).
Autologous hematopoietic stem cell transplantation did not control disability in progressive multiple sclerosis (MS) patients with advanced disability and low relapse activity, observational data showed. (Journal of Neurology, Neurosurgery & Psychiatry)
Peripheral blood immune signatures suggested there may be three MS subtypes, each associated with a distinct disease trajectory. (Science Translational Medicine)
Carrying two APOE4 alleles was linked with damaging lipid droplets in Alzheimer’s disease microglia. (Nature)
The Alzheimer’s Association updated its annual facts and figures book, reporting that nearly 7 million Americans have Alzheimer’s disease.
Abbott said it received FDA clearance for its i-STAT TBI cartridge, a whole-blood rapid test to evaluate patients with concussion at the bedside. Previous tests were cleared for use only with serum or plasma.
Diabetes, air pollution, and alcohol intake frequency were the most deleterious modifiable risk factors for brain regions vulnerable to aging and disease, an analysis showed. (Nature Communications)
Migraine and other nontraditional risk factors contributed to stroke incidence in young men and women. (Circulation: Cardiovascular Quality and Outcomes)
Sudden cardiac death and ventricular arrhythmia did not occur more frequently in patients who were newly prescribed levetiracetam versus oxcarbazepine for seizures. (Neurology)
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