The effectiveness of CAR T cell therapy against a variety of cancers, including solid tumors, could be boosted greatly by using CRISPR-Cas9 technology to knock out the gene for CD5, a protein found on the surface of T cells, according to a preclinical study from investigators at the University of Pennsylvania’s Perelman School of Medicine and Abramson Cancer Center.
Mania and Menopause; ADHD Drugs Still Scarce; Era of Muscarinic Agonists?
Perimenopause was linked with an increased risk of developing mania and major depressive disorder — but not schizophrenia spectrum disorders — when compared with the