The “RNA world” hypothesis proposes that the earliest life on Earth may have been based on RNA -; a single-stranded molecule similar in many ways to DNA -; like some modern viruses. This is because, like DNA, RNA can carry genetic information, but, like a protein, it can also act as an enzyme, initiating or accelerating reactions.
Merck winds down TIGIT, LAG-3 programs meant to temper Keytruda erosion
After multiple clinical failures, it’s finally the end of the road for Merck’s TIGIT program. The company is dropping development of its anti-TIGIT candidate vibostolimab
December 18, 2024