Quantitative Alzheimer’s risk factors, including accelerated brain changes over time, were detectable in healthy individuals over age 50. (Nature Communications)
Traumatic brain injury was a risk factor linked with treatable incident neuropsychiatric and other medical conditions in subsequent years, a large study in California showed. (JAMA Network Open)
The ORCHESTRA proof-of-concept study of investigational minzasolmin for early Parkinson’s disease did not meet its primary and secondary clinical endpoints, UCB said.
Large-scale genetic studies showed that migraine shares genes with non-immune-related gastrointestinal disorders like irritable bowel syndrome. (Neurology Genetics)
In a randomized trial, transcutaneous auricular vagus nerve stimulation improved insomnia severity for people with chronic insomnia disorder. (JAMA Network Open)
Glymphatic dysfunction was linked with severity and progression of Creutzfeldt-Jakob disease (CJD) in a small study. (Neurology)
The ratio of plasma brain-derived tau to phosphorylated tau 217 improved CJD prognostication. (Alzheimer’s & Dementia)
Household smoking was linked with brain volumes in children with genetic risk for multiple sclerosis. (Journal of Neurology, Neurosurgery & Psychiatry)
Here’s how people with neurodegenerative diseases can cope with heat waves. (JAMA Neurology)
CMS issued a directive requiring Medicare Advantage plans to provide access to tofersen (Qalsody), a treatment for SOD1-amyotrophic lateral sclerosis (ALS) that received accelerated FDA approval, the ALS Association said.
What is the neurologist’s role in promoting brain health? (Neurology)
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