GLP-1 Drugs and Colonoscopy; GI Symptoms Post-COVID; Identifying High-Risk Barrett’s

A systematic review and meta-analysis of five studies suggested that patients on GLP-1 receptor agonists were more likely to have inadequate bowel preparation for colonoscopy. (American Journal of Gastroenterology)

Researchers in JAMA Surgery reviewed the management of perforated peptic ulcer.

While authors in Gastroenterology reviewed immune dysfunction and infection risk in advanced liver disease.

Endoscopic submucosal dissection in spray coagulation mode during treatment of early gastric neoplasms can help control bleeding and potentially streamline the procedure, a randomized trial from Japan suggested. (American Journal of Gastroenterology)

Could protein phosphatase 6 represent a therapeutic target for metabolic dysfunction-associated steatohepatitis (MASH)? (Journal of Hepatology)

Though icosabutate failed to meet its primary endpoint in a phase IIb randomized trial in MASH, researchers said improvements in fibrosis warrant further study of the FFAR1/FFAR4 agonist. (Journal of Hepatology)

Gastrointestinal (GI) symptoms may linger after a COVID-19 infection in kids, a retrospective cohort study showed. (JAMA Network Open)

About a decade after Helicobacter pylori eradication treatment, risk of gastric non-cardia adenocarcinoma approached that of the general population, a large cohort study from the five Nordic countries found. (Gastroenterology)

In children at genetic risk for celiac disease, higher dietary fiber intake during the first 2 years of life was associated with a lower risk of developing the condition, the observational TEDDY study found. (Gastroenterology)

Clinicians detailed a case of severe microscopic colitis after multiple sclerosis treatment with ocrelizumab (Ocrevus). (Inflammatory Bowel Diseases)

Esopredict, a novel validated methylation-based biomarker assay, could help distinguish high-risk Barrett’s esophagus from low-risk disease. (American Journal of Gastroenterology)

MedPage Today was at the Crohn’s & Colitis Congress last week: check out our coverage of the annual meeting here.

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