Intracellular journey: The penetration of antidepressants into cells, organelles, and membranes

Researchers in neuropsychopharmacology challenge conventional wisdom about antidepressants’ actions, revealing significant intracellular activity that influences their effectiveness. Utilizing advanced technologies, the study prompts a reevaluation of drug targeting and mechanisms, opening new avenues for treating depression.

Novel PARP1 Inhibitor Shows Promise in Breast Cancer

SAN DIEGO — Saruparib, an investigational selective PARP1 inhibitor, showed promising activity in patients with certain homologous recombination repair (HRR)-deficient breast cancers, while limiting toxicity,

April 10, 2024

Bayer’s $425M non-hormonal therapy for menopause symptoms clears first PhIII test

The crown jewel from Bayer’s 2020 buyout of women’s health biotech KaNDy Therapeutics has proven its worth in the clinic, meeting all primary and secondary

January 9, 2024

COVID-19 vaccines offer protection against long-term effects, study suggests

A new study in The BMJ explores how far vaccination averted PCC.

November 24, 2023

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