Mania and Menopause; ADHD Drugs Still Scarce; Era of Muscarinic Agonists?

Perimenopause was linked with an increased risk of developing mania and major depressive disorder — but not schizophrenia spectrum disorders — when compared with the late reproductive period. (Nature Mental Health)

Global issues like the economy and climate change are weighing on young people’s mental health. (New York Times)

Despite signs from the FDA that manufacturers were catching up to meet demand, drugs to treat attention deficit-hyperactivity disorder (ADHD) remain hard to find. (Axios)

Video game console ownership, along with increased game play, improved mental well-being among study participants in Japan, an analysis suggested. (Nature Human Behavior)

The insomnia drug suvorexant (Belsomra) did not significantly reduce the risk of delirium in older hospitalized adults, a placebo-controlled phase III trial found. (JAMA Network Open)

As an FDA decision nears on the muscarinic agonist xanomeline-trospium for schizophrenia — which could represent the first new class of drug approved for the condition in decades — PharmaVoice looks at similar products being tested in this setting.

In children under 6 years of age with post-traumatic stress disorder (PTSD), increased clinginess after the PTSD-inducing event was the most commonly reported symptom. (Scientific Reports)

During the perinatal and postpartum periods, the proportions of anxiety disorders, depressive disorders, and PTSD were higher among people with intellectual and developmental disabilities (IDD) compared to those without IDD. (JAMA Network Open)

Researchers detailed the value of conducting qualitative exit interviews with clinical trial patients with schizophrenia. (Frontiers in Psychiatry)

A Manhattan judge ruled that lawsuits claiming that fetal acetaminophen (Tylenol) exposure causes ADHD can’t go forward. (Reuters)

In a small trial, a self-guided cognitive behavioral therapy mobile app for young adults with anxiety disorders helped to reduce symptoms regardless of the type of incentive strategy used to promote engagement. (JAMA Network Open)

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