Last month, the European Medicines Agency began looking into reports of suicidal ideation and thoughts of self-harm by users of GLP-1 medicines such as Novo Nordisk’s Ozempic, Wegovy (both semaglutide) and Saxenda (liraglutide), and now other GLP-1 receptor agonists.
While the European investigation is ongoing, analyst group TD Cowen says its own analysis of the FDA’s adverse events database found that with the potential exception of Saxenda, there was “no obvious link” between incretin drugs and suicide-related events. Wegovy and Saxenda’s US labels do include warnings about suicidal behavior and ideation.
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