Meta Title: “Pacira BioSciences Inc Patent: Treating Spasticity with Cryogenic Cooling

According to GlobalData’s company profile on Pacira BioSciences, Cancer treatment biomarkers was a key innovation area identified from patents. Pacira BioSciences‘s grant share as of January 2024 was 52%. Grant share is based on the ratio of number of grants to total number of patents.

Method for treating spasticity in a patient’s limb using cryogenic cooling

Source: United States Patent and Trademark Office (USPTO). Credit: Pacira BioSciences Inc

A recently granted patent (Publication Number: US11865038B2) discloses a method for treating spasticity in a patient’s limb using a cryogenic cooling needle. The method involves inserting the needle through the skin surface to target tissue near a motor nerve associated with the spasticity. By delivering a treatment cycle with a cooling phase, the liquid from the cooling fluid vaporizes within the needle to provide cooling to the nerve, effectively treating the spasticity. The needle’s varying stiffness, flexibility, and bending strength at different portions allow for precise positioning and treatment of the nerve.

Furthermore, the method includes features such as a controlled treatment cycle by a processor, error flag response, temperature measurement with a sensor, and modulation of cooling fluid flow rate. The positioning of the needle near the nerve can be verified using anatomical sites, electrical nerve stimulation, or ultrasound. The cooling phase generates a cryozone of specific volume and duration, ensuring effective treatment. Additionally, the method involves thawing the tissue post-treatment to safely remove the needle without disrupting the target tissue. These innovative features make the method a promising approach for treating spasticity in patients, particularly in upper limbs, with a focus on precision, safety, and efficacy.

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