According to GlobalData’s company profile on Shanghai Junshi Bioscience, Personalized cancer vaccines was a key innovation area identified from patents. Shanghai Junshi Bioscience’s grant share as of April 2024 was 19%. Grant share is based on the ratio of number of grants to total number of patents.
Isotope-enriched compounds for improving drug delivery and efficacy
A recently granted patent (Publication Number: US11970490B2) discloses an isotope-enriched compound with a heavy isotope-enriched amide functional group. The compound is characterized by a high level of isotope-enrichment, ranging from about 90% to 100%, as determined using mass spectrometry. This compound is utilized in pharmaceutical compositions suitable for oral administration and is particularly effective in treating PI3K mediated diseases such as melanoma, colorectal adenoma, breast cancer (including HR+ and HER2- subtypes), and pancreatic cancer.
Moreover, the patent outlines methods of treatment involving the administration of the isotope-enriched compound either in free form or as part of a pharmaceutical composition. The therapeutic efficacy of the compound, ranging from 50 mg to 500 mg, with a specific dosage of 300 mg administered once daily, is highlighted. Additionally, the patent suggests combining the compound with fulvestrant for enhanced treatment outcomes. The disclosed compound’s high level of isotope-enrichment, about 94% or higher, further underscores its potential in effectively targeting PI3K mediated diseases, as specified in the patent claims.
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GlobalData, the leading provider of industry intelligence, provided the underlying data, research, and analysis used to produce this article.
GlobalData Patent Analytics tracks bibliographic data, legal events data, point in time patent ownerships, and backward and forward citations from global patenting offices. Textual analysis and official patent classifications are used to group patents into key thematic areas and link them to specific companies