Noted Neuroscientist Dies; Nasal Spray for Alzheimer’s Disease; Benign MS

Cognitive neuroscientist Eleanor Maguire, PhD, whose studies of London taxi drivers’ brains helped transform memory research, died at age 54 following a battle with spinal cancer. (New York Times)

A Massachusetts man became the first person to try intranasal foralumab under an expanded access program for people with moderate Alzheimer’s disease, Tiziana Life Sciences said.

Solid Biosciences reported positive initial data from a phase I/II study of SGT-003, an investigational gene therapy for Duchenne muscular dystrophy.

White children were nearly twice as likely as Black children to have genetic testing for autism, epilepsy, and global developmental delay. (Neurology)

The Alzheimer’s plasma biomarker phosphorylated tau 217 (p-tau217) showed the highest concordance with amyloid-beta and tau PET, but discordance had significant implications for clinical outcomes. (JAMA Neurology)

A history of infectious mononucleosis and modifiable lifestyle factors influenced the probability of a benign disease course in multiple sclerosis (MS), a comparative analysis suggested. (Journal of Neurology, Neurosurgery & Psychiatry)

Proposals to incorporate Alzheimer’s disease biomarkers into clinical practice require profound changes in how Alzheimer’s is perceived and managed, physicians and researchers said. (JAMA Neurology)

Exposure to at least 30 minutes of daily sunshine in the first year of life or during the second trimester of pregnancy was tied to lower relapse risk in pediatric-onset MS. (Neurology: Neuroimmunology & Neuroinflammation)

While the Dutch public supports the right to an assisted death for people with dementia, most physicians in the Netherlands refuse to provide it. (New York Times)

A 20-year-old Indian college student who won the Memory League World Championship discussed the “memory palace” he created to recall 80 random numbers in 13.5 seconds. (New York Times)

  • Judy George covers neurology and neuroscience news for MedPage Today, writing about brain aging, Alzheimer’s, dementia, MS, rare diseases, epilepsy, autism, headache, stroke, Parkinson’s, ALS, concussion, CTE, sleep, pain, and more. Follow

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