Chronic active antibody-mediated rejection (caAMR) is a common cause of allograft loss after transplantation, with no approved therapies. Clazakizumab, a monoclonal antibody that targets the inflammatory cytokine interleukin-6 (IL-6), stabilized kidney transplant recipients’ kidney function in a phase 2 trial.
Persistent or increasing breast density linked to higher cancer risk
Identifying patterns in breast density changes can improve breast cancer risk prediction, emphasizing the importance of longitudinal assessments in screening.