PRO-1107 by ProfoundBio Suzhou for Solid Tumor: Likelihood of Approval – Pharmaceutical Technology

GlobalData tracks drug-specific phase transition and likelihood of approval scores, in addition to indication benchmarks based off 18 years of historical drug development data. Attributes of the drug, company and its clinical trials play a fundamental role in drug-specific PTSR and likelihood of approval.

PRO-1107 overview

PRO-1107 is under development for the treatment of solid tumors, epithelial ovarian cancer, primary peritoneal cancer, fallopian tube cancer, endometrial cancer, triple negative breast cancer, non-small cell lung cancer, gastric cancer, gastroesophageal junction (GEJ) adenocarcinoma, esophageal squamous cell carcinoma, urothelial cancers including bladder cancer, ureter cancer and renal cancer. The drug candidate is an antibody drug conjugate (ADC), administered through intravenous route. It acts by targeting  Protein Tyrosine Kinase 7 (PTK7).

ProfoundBio Suzhou overview

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ProfoundBio Suzhou (ProfoundBio) discovers and develops antibody-drug conjugates and T-cell engagers for the treatment of cancer. The company is investigating PRO1184, a FOLR1 (folate receptor alpha) based antibody targeting solid tumors; and PRO1160 to treat renal cell cancer (RCC) and non-Hodgkin lymphoma (NHL) cancer. It is also evaluating PRO1107, PRO1109, PRO1135, PRO1173, PRO1103, PRO1106 and PRO1176 programs against solid tumors. The company focuses on developing drugs that deliver small molecule payloads to tumor cells and eradicate cancer by supporting the immune system. ProfoundBio is headquartered in Suzhou, Jiangsu, China.

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