Protein CVD Risk Score; Long-Term Arrhythmias With Epilepsy; Automated ASD Detection

Large-scale proteomics produced a protein risk score that modestly improved prediction of cardiovascular events over clinical risk factors alone. (JAMA)

A heightened long-term risk of cardiac arrhythmias was observed in people with epilepsy, namely those using carbamazepine and valproic acid. (European Heart Journal)

Any moderate or extreme pain post-myocardial infarction did not bode well for the longevity of heart attack survivors in the SWEDEHEART cohort. (Journal of the American Heart Association)

Assessed with a mouth rinse test, oral inflammation was associated with poor endothelial function — a potential contributor to future cardiovascular disease — but not arterial stiffness. (Frontiers in Oral Health)

In the attempt to achieve racial diversity in the nationwide All of Us cohort study, recruitment ended up leaning toward overrepresentation of Black people and underrepresentation of Asians and Hispanics. (JAMA Cardiology)

In people with diabetic kidney disease, the SGLT2 inhibitor canagliflozin (Invokana) dampened the cardiorenal stress biomarkers signaling progressive heart and kidney disease, the CREDENCE trialists found. (Circulation)

Abiomed is recalling the labeling for the Impella RP Flex with SmartAssist System Catheter to clarify precautions when treating patients whose anticoagulation clotting time is below the recommended value, the FDA announced.

Among the predictors of death within 5 years after getting a HeartMate 3 left ventricular assist device: elevated blood urea nitrogen, prior coronary artery bypass graft or valve procedure, hemocompatibility-related adverse events, ventricular arrhythmias, and a low estimated glomerular filtration rate. (Journal of the American College of Cardiology)

A review urges sex-specific research on areas that are related to women being less likely to be considered for heart transplantation. (JACC: Heart Failure)

People undergoing angioplasty showed a drug-drug interaction when concomitantly getting IV P2Y12 inhibition with cangrelor (Kengreal) and oral P2Y12 inhibition with prasugrel (Effient). (JACC: Cardiovascular Interventions)

The FDA says that more Cardiosave Hybrid and Rescue intra-aortic balloon pumps are under Class I recall due to unexpected shutdowns.

Among Spaniards with intracerebral hemorrhage, direct transfer to an endovascular treatment-capable stroke center resulted in worse outcomes compared with transfer to the nearest local stroke center, the RACECAT trial showed. (JAMA Neurology)

COVID-19 infection was linked to new-onset hypertension in a retrospective observational study from the Bronx, New York. (Hypertension)

A deep learning model was trained to find atrial septal defects (ASDs) based on 12-lead electrocardiography. (eClinicalMedicine)

CathVision said FDA cleared its PVI Analyzer and Signal Complexity artificial intelligence (AI) algorithms for use as part of the ECGenius electrophysiology recording system.

Viz.ai announced FDA approval of its Viz HCM module, an AI detection algorithm integrated into the Viz.ai Platform that flags hypertrophic cardiomyopathy.

Date rape allegations against Denver cardiologist Stephen Matthews, MD, were detailed at his preliminary hearing. (CBS News)

A rat study supports a galectin-3 protein inhibitor limiting scarring after myocardial infarction to stave off ventricular enlargement and progressive heart failure. (Cardiovascular Research)

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