An international research collaboration, led by Prof. Dr. Robert Grosse (Centre for Integrative Biological Signalling Studies and Institute of Clinical and Experimental Pharmacology and Toxicology, University of Freiburg), Dr. Libor Macurek (Institute of Molecular Genetics, Czech Academy of Sciences, Prague) and Dr. Zdenek Lansky (Institute of Biotechnology, Czech Academy of Sciences, Prague) has uncovered a new mechanism of the crosstalk between microtubules and actin cytoskeleton during cell division and revealed unique characteristics of the previously unexplored protein FAM110A.
US FDA grants breakthrough therapy status for Nuvalent’s NVL-655
NVL-655 is intended to treat locally advanced or metastatic ALK-positive NSCLC patients previously treated with two or more ALK TKIs. Credit: Sebastian Kaulitzki / Shutterstock.com.