The combination of Seagen’s Tukysa and Roche’s Kadcyla cut the risk of disease progression or death by 36% in HER2-positive breast cancer patients with brain metastases compared to Kadcyla alone.
The Phase III trial, sponsored by Seagen, is one of the few big studies prospectively designed to evaluate the effects of new treatments in breast cancer patients with brain metastases, said Sara Hurvitz, head of hematology and oncology at the University of Washington and SVP of clinical research at the Fred Hutchinson Cancer Center, in a press statement.
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