Stress and Strokes; Gene Hackman’s CVD Death; PFO Closure for the Nickel-Sensitive

An association between stress and cryptogenic ischemic stroke was observed in young women, but not young men, in a case-control study. (Neurology)

Pooled cohort data suggested a likely causal relationship between stroke and all-cause dementia, while genetic susceptibility for ischemic heart disease was linked to incident vascular dementia. (European Journal of Preventive Cardiology)

Also, people with high cardiovascular health scores typically had lower levels of neurofilament light chain, a serum biomarker of neurodegeneration, according to a cohort study. (JAMA Network Open)

Actor Gene Hackman’s pacemaker had shown atrial fibrillation on the day he probably died of heart disease. (AP)

In the MESA cohort, the link between carotid artery plaque and incident atherosclerotic cardiovascular disease events was most notable among younger patients, especially for women. (JAMA Cardiology)

Building on the link between cigarette smoking and subclinical atherosclerosis, observational data suggested that former smokers had biomarkers return to mostly normal after 30 years, other than a persistently elevated coronary artery calcium score. (Journal of the American College of Cardiology)

For survivors of heart attack due to spontaneous coronary artery dissection, treatment with oral anticoagulation or potent antiplatelet therapy was tied to adverse cardiovascular outcomes in a cohort study. (European Heart Journal)

After transcatheter patent foramen ovale (PFO) closure, patients with nickel hypersensitivity were more likely to develop device syndrome, but this did not translate into more arrhythmias, bleeding, or stroke, a randomized trial found. (Circulation: Cardiovascular Interventions)

A target trial emulation study supported the primary prevention benefits of statins in older people with chronic kidney disease and elevated low-density lipoprotein cholesterol. (Lancet-Healthy Longevity)

In the SERENADE trial of patients with heart failure with preserved/mildly reduced ejection fraction and pulmonary vascular disease, macitentan neither reduced N-terminal pro-B-type natriuretic peptide nor improved heart failure outcomes. (Circulation: Heart Failure)

Women undergoing modern breast radiation treatment appeared to have changes in cardiac function suggestive of early heart failure with preserved ejection fraction, according to a longitudinal cohort study. (JACC: CardioOncology)

Pregnant women with higher copper and manganese levels in their blood were at lower risk of subsequently developing high blood pressure (BP) by mid-life, a prospective cohort study showed. (Hypertension)

Teenagers sleeping less than 7.7 hours in a sleep lab were more likely to have elevated BP, according to research highlighted by the American Heart Association.

The American Society of Echocardiography released guidelines for echocardiographic right heart assessment, with special considerations for pulmonary hypertension.

Experiments in piglets provided preclinical evidence for the concept of partial heart transplants for growing infants. (JACC: Basic to Translational Science)

Former cardiologist Stephen Matthews had his medical license revoked by the Colorado Medical Board several months after a rape conviction sent him to prison for 158 years. (CBS News)

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