Asthma patients experience respiratory distress due to allergens like house dust mites or pollen. However, the various triggers for asthma share a common pathway involving the release of proteins called type-2 cytokines by Type-2 helper T (Th2) cells and group-2 innate lymphoid cells (ILC2s). Both Th2 and ILC2 require high amounts of GATA-binding protein 3 (GATA3) for their maturation.
Synlogic’s phenylketonuria therapy gains FDA fast track status
Phenylketonuria is caused by inherited mutations that affect Phe disintegration. Credit: Saiful52 via Shutterstock.com. The US Food and Drug Administration (FDA) has awarded fast track designation to