Scientists have generated a comprehensive map of the gene targets regulated by the transcription factors HNF4A and HNF1A in human pancreatic beta cells and liver cells. Published in the journal Nature Communications, the study revealed common and tissue-specific molecular pathways regulated by HNF4A and HNF1A, two proteins that possess important functions governing the development and function of the pancreas and liver.
Trailing Akero and 89bio, Boston Pharmaceuticals posts early data on its NASH injection
In an early-stage study, Boston Pharmaceuticals’ injection reduced indicators of NASH, a fatty liver disease. The treatment is one of a handful of investigational drugs
June 22, 2023