TAVR Pioneer Dies; Allograft Rejection Criteria Need Work; Overeating Protein & CVD

Alain Cribier, MD, who performed the first transcatheter aortic valve replacement (TAVR) in 2002, died last week at age 79, the American College of Cardiology announced.

Higher lipoprotein(a) went hand in hand with increased cardiovascular risk independent of high-sensitivity C-reactive protein level, both in primary and secondary prevention cohorts. (JAMA Cardiology)

U.S. hospital prices for coronary artery bypass grafting surgery vary substantially, and a more expensive procedure is not associated with better quality of care. (Journal of the American Heart Association)

A strategy of IV tirofiban (Aggrastat) before endovascular treatment (EVT) for acute ischemic stroke fared similarly to alteplase bridging with EVT in patients with intracranial large vessel occlusions, based on a pooling of two randomized trials. (Stroke)

Acupuncture was associated with fewer strokes in people with rheumatoid arthritis. Could a decrease in cytokines explain the finding? (BMJ Open)

Indigenous populations in highly developed countries tend to have disproportionately high stroke rates. (Neurology)

In a pilot study, automatic mechanical ventilators performed numerically better than manual bag ventilation for restoring spontaneous circulation during CPR of out-of-hospital cardiac arrest. (CHEST)

Current histological grading criteria for endomyocardial biopsy samples inadequately describe cardiac allograft rejection, the leading cause of early graft failure after heart transplant. (Circulation: Heart Failure)

Use of primary prevention implantable cardioverter-defibrillators was not hindered by the mandate to have Medicare reimbursement contingent on shared decision-making. (JAMA Internal Medicine)

Observational data suggest thoracotomy-based HeartMate 3 left ventricular assist device implant surgeries are non-inferior to standard full sternotomy. (Journal of Thoracic and Cardiovascular Surgery)

Survey of cardiologists reveals cognitive biases that make them view procedures with a high level of mechanistic intuitiveness as highly effective — or conversely, dismiss effective therapies that are not fully understood. (Circulation: Cardiovascular Quality and Outcomes)

Women can exercise less often than men and still receive greater cardiovascular benefits from moderate to vigorous physical activity. (Journal of the American College of Cardiology)

Ultra-processed food consumption correlated with cardiovascular events in a meta-analysis counting over 1 million participants. (eClinicalMedicine)

In a Nordic study of adolescents and young adults, a booster COVID mRNA vaccine was associated with more myocarditis — though the absolute risk was still low. (European Heart Journal)

A news segment on the rationale behind an initiative to train more Black cardiologists. (NBC News)

Scientists suggest a mechanism for why people who eat excessive protein are prone to more atherosclerotic plaque formation. (Nature Metabolism)

One group has developed a protocol to induce human pluripotent stem cells to differentiate into functional heart valve cells. (Circulation)

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