Vir Biotechnology Inc Patent: Monoclonal Antibody for Staphylococcus Aureus Infection

According to GlobalData’s company profile on Vir Biotechnology, Peptide pharmacophores was a key innovation area identified from patents. Vir Biotechnology‘s grant share as of April 2024 was 21%. Grant share is based on the ratio of number of grants to total number of patents.

Monoclonal antibody for treating staphylococcus aureus infection

Source: United States Patent and Trademark Office (USPTO). Credit: Vir Biotechnology Inc

A recently granted patent (Publication Number: US11970527B2) discloses a composition comprising an antibody or antigen-binding fragment that specifically binds to a Staphylococcus aureus (S. aureus) ClfA protein, along with an antibody or fragment that targets an S. aureus alpha toxin (AT) protein. The composition includes specific amino acid sequences for the variable heavy chain (VH), variable light chain (VL), and heavy chain constant domain, providing a detailed framework for the antibodies’ binding specificity.

Furthermore, the patent claims encompass variations in the heavy chain constant domain, mutations like the YTE mutation, and the use of IgG1 antibodies for targeting the S. aureus ClfA and AT proteins. The detailed sequences provided in the claims offer a precise understanding of the composition’s design and functionality, emphasizing the specificity and efficacy of the antibodies in targeting these key S. aureus proteins. The patent’s focus on specific amino acid sequences and mutations highlights the innovative approach taken in developing antibodies for combating S. aureus infections.

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GlobalData, the leading provider of industry intelligence, provided the underlying data, research, and analysis used to produce this article.

GlobalData Patent Analytics tracks bibliographic data, legal events data, point in time patent ownerships, and backward and forward citations from global patenting offices. Textual analysis and official patent classifications are used to group patents into key thematic areas and link them to specific companies