Super-agers like Norman Lear, who died last month at age 101, show what successful cognitive aging looks like. A study at the Albert Einstein College of Medicine that’s recruiting 10,000 super-agers and their adult children may reveal more. (Chicago Sun-Times)
Does President Joe Biden have the makings of a super-ager? (The Hill)
Expanded T lymphocytes in the cerebrospinal fluid of people with early multiple sclerosis were specific for Epstein-Barr virus (EBV)-infected B cells. (PNAS)
Magnesium-ibogaine therapy improved functional outcomes among Special Operations Forces veterans with traumatic brain injuries. (Nature Medicine)
Researchers discovered five biological variants of Alzheimer’s disease that had different clinical outcomes, survival times, and patterns of brain atrophy. (Nature Aging)
A previously unknown mutation in the SHLP2 mitochondrial microprotein appeared to be highly protective against Parkinson’s disease. (Molecular Psychiatry)
Anavex Life Sciences reported mixed results from its phase II/III EXCELLENCE study of investigational Anavex 2-73 (blarcamesine) in pediatric Rett Syndrome.
A phase Ib study showed the investigational gene therapy AB-1005 was well tolerated in Parkinson’s patients, Bayer and AskBio said.
The calcium channel blocker verapamil (Verelan) eased symptoms in a mouse model of myotonic dystrophy type 1. (Journal of Clinical Investigation)
Neural injury markers measured 6 months after hospitalization with SARS-CoV-2 infection were not associated with post-acute COVID neuropsychiatric symptoms. (Brain Communications)
Macrophages tagged with gadolinium-loaded anisotropic micropatches (GLAMs) helped researchers identify animals exposed to traumatic brain injury. (Science Translational Medicine)
A soft robotic suit stopped gait freezing for a 73-year-old man with Parkinson’s disease. (Nature Medicine)
The FDA approved the Percept rechargeable neurostimulator and deep brain stimulation system for movement disorders and epilepsy, Medtronic said.
The prevalence of tinnitus was 11% in the U.S., the 2014 National Health Interview Survey showed. (Lancet Regional Health-Americas)
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